David Bredt headshot

David Bredt, M.D., Ph.D.

Executive Partner

Executive Partners

San Francisco Office

Dr. David S. Bredt is a proven leader in neurology research and development and has held key senior roles at Eli Lilly and Company and Johnson & Johnson.

Before joining MPM, David was Site Head for Johnson & Johnson’s R&D Campus in La Jolla, which focuses on Neuroscience, Immunology and Biotechnology and is the original JLABS incubator for emerging healthcare companies. He was Global Head of Neuroscience Discovery at Johnson & Johnson where he had line management responsibility for neuroscience biology, biomarkers, and external innovation activities. His discovery group delivered numerous small and large molecule clinical candidates for Alzheimer’s disease, major depression, schizophrenia and epilepsy.

David joined Eli Lilly and Company as Vice President of Integrative Biology in August 2004 and became Vice President of Neuroscience Discovery and Early Development a few years later. As head of neuroscience research at Eli Lilly, David’s group was responsible Discovery through Phase 2 programs in Neurology, Psychiatry, Migraine, and Pain indications. His group prosecuted numerous small and large molecules that entered preclinical and clinical development including galcanezumab / Emgality, which is now approved for preventative treatment of migraine.

David graduated summa cum laude in Chemistry at Princeton University. He received his M.D. and Ph.D. at Johns Hopkins University School of Medicine, where he trained with Dr. Solomon H. Snyder. After graduation, Bredt was Professor of Physiology at the University of California, San Francisco for ten years. His research on nitric oxide, glutamate receptor signaling, and synaptic plasticity has yielded ~225 papers, which have been cited ~75,000 times in the scientific literature. He served on the Medical Advisory Committee for the Muscular Dystrophy Association, he was an Established Investigator for the American Heart Association, and he was a National Young Investigator for the National Science Foundation.